In silico and in vitro: identifying new drugs.

@article{Pauli2008InSA,
  title={In silico and in vitro: identifying new drugs.},
  author={Ivani Pauli and Lu{\'i}s Fernando S. M. Timmers and Rafael A. Caceres and Milena Botelho Pereira Soares and Walter Filgueira de Azevedo},
  journal={Current drug targets},
  year={2008},
  volume={9 12},
  pages={
          1054-61
        }
}
Drug development is a high cost and laborious process, requiring a number of tests until a drug is made available in the market. Therefore, the use of methods to screen large number of molecules with less cost is crucial for faster identification of hits and leads. One strategy to identify drug-like molecules is the search for molecules able to interfere with a protein function, since protein interactions control most biological processes. Ideally the use of in silico screenings would make drug… CONTINUE READING

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