In silico analysis of TTR gene (coding and non-coding regions, and interactive network) and its implications in transthyretin-related amyloidosis.


INTRODUCTION Transthyretin (TTR)-related amyloidosis is a life-threatening disease. Currently, several questions about the pathogenic mechanisms of TTR-related amyloidosis remain unanswered. METHODS We have investigated various TTR-related issues using different in silico approaches. RESULTS Using an amino acid similarity-based analysis, we have… (More)
DOI: 10.3109/13506129.2014.900487


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