In silico Identification of potential 5α‒reductase inhibitors for prostatic diseases: QSAR modelling, molecular docking, and pre ADME predictions

  title={In silico Identification of potential 5$\alpha$‒reductase inhibitors for prostatic diseases: QSAR modelling, molecular docking, and pre ADME predictions},
  author={Neelima Dhingra},
  journal={MOJ Drug Design Development \& Therapy},
  • N. Dhingra
  • Published 12 June 2018
  • Biology, Medicine
  • MOJ Drug Design Development & Therapy
Steroids assume an essential part in a several processes, ranging from the differentiation, growth, development, physiological and regenerative functions in the human body,1 because of their ability to cross membrane easily.2 Steroids as well as their derivatives have the potential to be developed as drugs for the treatment of a large number of diseases including cardiovascular, autoimmune diseases, brain tumours, breast cancer, osteoarthritis, prostate cancer etc.3‒6 The promise of using… 



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