In silico Activity Analysis of Saponins and 2, 5-Piperazinedione from Marine Organism against Murine Double Minute-2 Inhibitor and Procaspase-3 Activator

@article{Yanuar2018InSA,
  title={In silico Activity Analysis of Saponins and 2, 5-Piperazinedione from Marine Organism against Murine Double Minute-2 Inhibitor and Procaspase-3 Activator},
  author={A. Yanuar and I. Pratiwi and Rezi Riadhi Syahdi},
  journal={Journal of Young Pharmacists},
  year={2018},
  volume={10}
}
  • A. Yanuar, I. Pratiwi, Rezi Riadhi Syahdi
  • Published 2018
  • Chemistry
  • Journal of Young Pharmacists
  • Objective: Cancer is a disease that can occur because of apoptosis failure. One of the causes of apoptosis failure is the presence of MDM2 inhibiting the activity of p53 so procaspase-3 could not be activated to caspase-3. Currently, the treatment of cancer has been applied widely, but more effective treatment always needed because cancer has been mutated. One of the treatments is the search for natural resources that come from the sea. The pursuit of the bioactive compound from marine… CONTINUE READING
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