In silico ADME/T modelling for rational drug design.

@article{Wang2015InSA,
  title={In silico ADME/T modelling for rational drug design.},
  author={Yulan Wang and Jing Xing and Yuan Xu and Nannan Zhou and Jianlong Peng and Zhaoping Xiong and Xian Liu and Xiaomin Luo and Cheng Luo and Kaixian Chen and Mingyue Zheng and Hualiang Jiang},
  journal={Quarterly reviews of biophysics},
  year={2015},
  volume={48 4},
  pages={
          488-515
        }
}
In recent decades, in silico absorption, distribution, metabolism, excretion (ADME), and toxicity (T) modelling as a tool for rational drug design has received considerable attention from pharmaceutical scientists, and various ADME/T-related prediction models have been reported. The high-throughput and low-cost nature of these models permits a more streamlined drug development process in which the identification of hits or their structural optimization can be guided based on a parallel… CONTINUE READING

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