In search for symmetries in the metabolism of cancer.

@article{Gatto2016InSF,
  title={In search for symmetries in the metabolism of cancer.},
  author={Francesco Gatto and Jens B Nielsen},
  journal={Wiley interdisciplinary reviews. Systems biology and medicine},
  year={2016},
  volume={8 1},
  pages={23-35}
}
Even though aerobic glycolysis, or the Warburg effect, is arguably the most common trait of metabolic reprogramming in cancer, it is unobserved in certain tumor types. Systems biology advocates a global view on metabolism to dissect which traits are consistently reprogrammed in cancer, and hence likely to constitute an obligate step for the evolution of cancer cells. We refer to such traits as symmetric. Here, we review early systems biology studies that attempted to reveal symmetric traits in… CONTINUE READING
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