In patients with aortic stenosis increased flow-mediated dilation is independently associated with higher peak jet velocity and lower asymmetric dimethylarginine levels.

@article{Schumm2011InPW,
  title={In patients with aortic stenosis increased flow-mediated dilation is independently associated with higher peak jet velocity and lower asymmetric dimethylarginine levels.},
  author={Julia Schumm and Stephanie Luetzkendorf and Wilma Rademacher and Marcus Franz and Christiane Schmidt-Winter and Michael Kiehntopf and Hans R. Figulla and Bernhard R. Brehm},
  journal={American heart journal},
  year={2011},
  volume={161 5},
  pages={893-9}
}
BACKGROUND Recently, it has been shown that endothelial dysfunction and aortic stenosis (AS) share several risk factors. Endothelial function represents a crucial factor for the regulation of vascular tonus and its malfunction influences the formation of thrombosis and inflammation. However, the role of endothelial dysfunction in AS remains unclear. METHODS Echocardiographic, clinical, and laboratory data of 34 patients (age 74.5 ± 7.9 years, 20 men) with at least moderate AS (peak jet… CONTINUE READING

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