In ovo treatment with CpG oligodeoxynucleotides decreases colonization of Salmonella enteriditis in broiler chickens.

@article{Mackinnon2009InOT,
  title={In ovo treatment with CpG oligodeoxynucleotides decreases colonization of Salmonella enteriditis in broiler chickens.},
  author={Kathryn M Mackinnon and Haiqi He and Christina L. Swaggerty and Jackson L McReynolds and Kenneth J. Genovese and Sara E. Duke and Jessica R. Nerren and Michael H. Kogut},
  journal={Veterinary immunology and immunopathology},
  year={2009},
  volume={127 3-4},
  pages={371-5}
}
Induction of the innate immune response in newly hatched chickens is important for limiting infections with bacteria, such as Salmonella enterica serovar Enteriditis (SE). CpG oligodeoxynucleotides (CpG-ODN) can stimulate the innate immune response of young chickens. Therefore, we examined the effectiveness of CpG-ODN administered in ovo on intestinal colonization by SE and the ability to modulate the function of heterophils in young chickens. Heterophils were isolated from 2-day-old chickens… CONTINUE READING