In ovo effects of perfluorohexane sulfonate and perfluorohexanoate on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos.

@article{Cassone2012InOE,
  title={In ovo effects of perfluorohexane sulfonate and perfluorohexanoate on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos.},
  author={Cristina G. Cassone and Viengtha Vongphachan and Suzanne Chiu and Kim L Williams and Robert J Letcher and Eric Pelletier and Doug Crump and Sean W. Kennedy},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2012},
  volume={127 1},
  pages={216-24}
}
Perfluoroalkyl acids (PFAAs), specifically perfluorinated sulfonates and carboxylates, are synthetic substances known for their chemical stability, resistance to degradation, and potential to biomagnify in food chains. The toxicological and biological effects of PFAAs in avian species are not well characterized, although there is some evidence to suggest that they can impact neurodevelopment and hatching success. Our laboratory recently reported significant effects of perfluorohexane sulfonate… CONTINUE READING