In obesity and weight loss, all roads lead to the mighty macrophage.

@article{Eagle2010InOA,
  title={In obesity and weight loss, all roads lead to the mighty macrophage.},
  author={Alex Red Eagle and Ajay Chawla},
  journal={The Journal of clinical investigation},
  year={2010},
  volume={120 10},
  pages={3437-40}
}
Obesity is associated with infiltration of white adipose tissue (WAT) by macrophages, which contributes to the development of insulin resistance. In this issue of the JCI, Kosteli and colleagues demonstrate that weight loss is unexpectedly also associated with rapid, albeit transient, recruitment of macrophages to WAT and that this appears to be related to… CONTINUE READING

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