In-line SPE-CE using a fritless bead string design--application for the analysis of organic sulfonates including inline SPE-CE-MS for APTS-labeled glycans.


Despite many advantages like high separation efficiency CE comprises the main limitation of low concentration sensitivity, when compared to HPLC. In-line SPE is an efficient way to increase concentration sensitivity. Here, a fritless in-line-SPE-CE-MS method was developed in order to analyze anions of strong acids. Mixed-mode (weak anion exchange and RP… (More)
DOI: 10.1002/elps.201300388

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