In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.

@article{Bourreau2009InLD,
  title={In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.},
  author={Eliane Bourreau and Catherine Ronet and Edith Darsissac and Marie-Claire Lise and Dominique Sainte Marie and Emmanuel Clity and Fabienne Tacchini-Cottier and Pierre Couppi{\'e} and Pascal Launois},
  journal={The Journal of infectious diseases},
  year={2009},
  volume={199 4},
  pages={576-9}
}
The presence of intralesional natural regulatory T cells, characterized by the expression of Foxp3 mRNA, was analyzed in patients with localized leishmaniasis due to Leishmania guyanensis infection that was unresponsive to treatment with pentamidine isethionate. Foxp3 mRNA levels were associated with unresponsiveness to treatment among patients with a lesion duration of 1 month, but this association was not observed among patients with a lesion duration of <1 month. In conclusion, high… CONTINUE READING
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