In-depth analysis of the human tear proteome.

@article{Zhou2012IndepthAO,
  title={In-depth analysis of the human tear proteome.},
  author={Lei Zhou and Shao Zhen Zhao and Siew Kwan Koh and Liyan Chen and Candida Vaz and Vivek Tanavde and Xiao Rong Li and Roger W. Beuerman},
  journal={Journal of proteomics},
  year={2012},
  volume={75 13},
  pages={
          3877-85
        }
}
The tears, a critical body fluid of the surface of the eye, contain an unknown number of molecules including proteins/peptides, lipids, small molecule metabolites, and electrolytes. There have been continued efforts for exploring the human tear proteome to develop biomarkers of disease. In this study, we used the high speed TripleTOF 5600 system as the platform to analyze the human tear proteome from healthy subjects (3 females and 1 male, average age: 36±14). We have identified 1543 proteins… CONTINUE READING
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