In colchicine-treated rats, cellular distribution of AQP-1 in convoluted and straight proximal tubule segments is differently affected

@article{Mirela2000InCR,
  title={In colchicine-treated rats, cellular distribution of AQP-1 in convoluted and straight proximal tubule segments is differently affected},
  author={Baus Mirela and M Mil{\'a} and Dennis L. Brown and Sabolic Ivan},
  journal={Pfl{\"u}gers Archiv},
  year={2000},
  volume={439},
  pages={321-330}
}
In cells along the nephron, the recycling of various components between the plasma membrane and intracellular organelles by vesicle trafficking depends on intact microtubules (MT). Previous studies of rats treated with the MT-disrupting drug colchicine showed that some brush-border membrane (BBM) transporters in renal proximal convoluted tubule cells (PCTC) become internalized in numerous vesicles randomly scattered in the cytoplasm. In this study, we compare the intracellular distribution of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Role of microtubules in the rapid regulation of renal phosphate transport in response to acute alterations in dietary phosphate content

  • M Lötscher, B Kaissling, J Biber, H Murer, M Levi
  • J Clin Invest
  • 1997

Effects of microtubule disruption on endocytosis , membrane recycling and polarized distribution of Aquaporin - 1 and gp 330 in proximal tubule cells

  • Elkjaer M-L, H Birn, P Agre, EI Christensen, S Nielsen
  • Eur J Cell Biol
  • 1995

Similar Papers

Loading similar papers…