In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides.

@article{Fraune2010InAE,
  title={In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides.},
  author={Sebastian Fraune and R. J. M. Augustin and Friederike Anton-Erxleben and J{\"o}rg Wittlieb and Christoph Gelhaus and Vladimir B Klimovich and Marina P Samoilovich and Thomas C G Bosch},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 42},
  pages={18067-72}
}
Early embryos of many organisms develop outside the mother and are immediately confronted with myriads of potential colonizers. How these naive developmental stages control and shape the bacterial colonization is largely unknown. Here we show that early embryonic stages of the basal metazoan Hydra are able to control bacterial colonization by using maternal antimicrobial peptides. Antimicrobial peptides of the periculin family selecting for a specific bacterial colonization during embryogenesis… CONTINUE READING