In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.

@article{Tchakout2006InAB,
  title={In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.},
  author={Virginia L Tchakout{\'e} and Simon Paul Graham and Siv Aina Jensen and Benjamin L. Makepeace and Charles K. Nfon and Leo M. Njongmeta and Sara Lustigman and Peter AI Enyong and Vincent N. Tanya and Albert Edward Bianco and Alexander J. Trees},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 15},
  pages={5971-6}
}
Onchocerciasis (river blindness) is a major parasitic disease of humans in sub-Saharan Africa caused by the microfilarial stage of the nematode Onchocerca volvulus. Using Onchocerca ochengi, a closely related species which infects cattle and is transmitted by the same black fly vector (Simulium damnosum sensu lato) as O. volvulus, we have conducted longitudinal studies after either natural field exposure or experimental infection to determine whether, and under what circumstances, protective… CONTINUE READING