In Vivo Mechanisms Underlying Dopamine Release from Rat Nigrostriatal Terminals: II. Studies Using Potassium and Tyramine

@article{Fairbrother1990InVM,
  title={In Vivo Mechanisms Underlying Dopamine Release from Rat Nigrostriatal Terminals: II. Studies Using Potassium and Tyramine},
  author={Iain S. Fairbrother and Gordon William Arbuthnott and John S. Kelly and Steven P. Butcher},
  journal={Journal of Neurochemistry},
  year={1990},
  volume={54}
}
Abstract: The brain microdialysis technique has been used to examine the in vivo effects of potassium and tyramine on dopamine (DA) release and metabolism in the striatum of halothane‐anaesthetised rats. Increasing the concentration of potassium perfusing the dialysis probe (30–120 mM) induced a dose‐related efflux of DA. A dose‐related release of DA was also observed following addition of tyramine (1–100 μM) to the perfusing buffer. High concentrations of potassium were found to reduce the… 
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References

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