In Vivo Long-Term Monitoring of Circulating Tumor Cells Fluctuation during Medical Interventions

@article{Juratli2015InVL,
  title={In Vivo Long-Term Monitoring of Circulating Tumor Cells Fluctuation during Medical Interventions},
  author={M. Juratli and E. Siegel and D. Nedosekin and M. Sarimollaoglu and A. Jamshidi‐Parsian and C. Cai and Y. Menyaev and J. Suen and E. Galanzha and V. Zharov},
  journal={PLoS ONE},
  year={2015},
  volume={10}
}
The goal of this research was to study the long-term impact of medical interventions on circulating tumor cell (CTC) dynamics. We have explored whether tumor compression, punch biopsy or tumor resection cause dissemination of CTCs into peripheral blood circulation using in vivo fluorescent flow cytometry and breast cancer-bearing mouse model inoculated with MDA-MB-231-Luc2-GFP cells in the mammary gland. Two weeks after tumor inoculation, three groups of mice were the subject of the following… Expand
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