In Vivo Initiation of Clock Gene Expression Rhythmicity in Fetal Rat Suprachiasmatic Nuclei

@inproceedings{Houdek2014InVI,
  title={In Vivo Initiation of Clock Gene Expression Rhythmicity in Fetal Rat Suprachiasmatic Nuclei},
  author={Pavel V. Houdek and Alena Sumov{\'a} and Henrik Oster},
  booktitle={PloS one},
  year={2014}
}
The mammalian suprachiasmatic nuclei (SCN) and their intrinsic rhythmicity develop gradually during ontogenesis. In the rat, the SCN forms between embryonic day (E) 14 and E17, with gestation terminating at E21-22. Overt SCN rhythmicity is already present in the late embryonic stage. The aim of the present study was to determine when the fetal SCN clock develops in vivo and whether overt rhythmicity results from a functional fetal clock. To achieve this goal, the prenatal development of… CONTINUE READING

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Development of the suprachiasmatic nucleus

RY Moore
1991
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Highly Influenced

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