In Vivo Imaging of Cerebral Dopamine D3 Receptors in Alcoholism

Abstract

Animal studies support the role of the dopamine D3 receptor (DRD3) in alcohol reinforcement or liking. Sustained voluntary alcohol drinking in rats has been associated with an upregulation of striatal DRD3 gene expression and selective blockade of DRD3 reduces ethanol preference, consumption, and cue-induced reinstatement. In vivo measurement of DRD3 in the… (More)
DOI: 10.1038/npp.2014.18

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