In Vivo High-Resolution 7 Tesla MRI Shows Early and Diffuse Cortical Alterations in CADASIL

@inproceedings{Guio2014InVH,
  title={In Vivo High-Resolution 7 Tesla MRI Shows Early and Diffuse Cortical Alterations in CADASIL},
  author={F De Guio and Sonia Reyes and Alexandre Vignaud and Marco Duering and Stefan Ropele and Edouard Duchesnay and Hugues Chabriat and Eric Jouvent},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND AND PURPOSE Recent data suggest that early symptoms may be related to cortex alterations in CADASIL (Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy), a monogenic model of cerebral small vessel disease (SVD). The aim of this study was to investigate cortical alterations using both high-resolution T2* acquisitions obtained with 7 Tesla MRI and structural T1 images with 3 Tesla MRI in CADASIL patients with no or only mild symptomatology… CONTINUE READING