In Vivo Flow Cytometry of Circulating Tumor-Associated Exosomes

@article{Nolan2016InVF,
  title={In Vivo Flow Cytometry of Circulating Tumor-Associated Exosomes},
  author={Jacqueline Nolan and Mustafa Sarimollaoglu and Dmitry Nedosekin and Azemat Jamshidi‐Parsian and Ekaterina I. Galanzha and Rajshekhar A. Kore and Robert J. Griffin and Vladimir P. Zharov},
  journal={Analytical Cellular Pathology (Amsterdam)},
  year={2016},
  volume={2016}
}
Circulating tumor cells (CTCs) demonstrated the potential as prognostic markers of metastatic development. However, the incurable metastasis can already be developed at the time of initial diagnosis with the existing CTC assays. Alternatively, tumor-associated particles (CTPs) including exosomes can be a more valuable prognostic marker because they can be released from the primary tumor long before CTCs and in larger amount. However, little progress has been made in high sensitivity detection… 

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