In Vivo FRET Imaging Revealed a Regulatory Role of RanGTP in Kinetochore-Microtubule Attachments via Aurora B Kinase

Abstract

Under the fluctuating circumstances provided by the innate dynamics of microtubules and opposing tensions resulted from microtubule-associated motors, it is vital to ensure stable kinetochore-microtubule attachments for accurate segregation. However, a comprehensive understanding of how this regulation is mechanistically achieved remains elusive. Using our… (More)
DOI: 10.1371/journal.pone.0045836

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@inproceedings{Lee2012InVF, title={In Vivo FRET Imaging Revealed a Regulatory Role of RanGTP in Kinetochore-Microtubule Attachments via Aurora B Kinase}, author={Yoke-Peng Lee and Chi-Hang Wong and Kheng-Sze Chan and S Lai and C Koh and Hoi-Yeung Li}, booktitle={PloS one}, year={2012} }