In Vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays

  title={In Vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays},
  author={Andr{\'e} Mercanzini and Philippe Colin and Jean-Charles Bensadoun and Anne Bertsch and Philippe Renaud},
  journal={IEEE Transactions on Biomedical Engineering},
The goal of this experiment was to determine the electrical properties of the tissue reaction to implanted microelectrode arrays. We describe a new method of analyzing electrical impedance spectroscopy data to determine the complex impedance of the tissue reaction as a function of postimplantation time. A model is used to extract electrical model parameters of the electrode-tissue interface, and is used to isolate the impedance of the tissue immediately surrounding the microelectrode. The… CONTINUE READING
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