In Vivo Effects of Diosgenin on the Activity of Some Drug-metabolizing Enzyme Systems

@inproceedings{KondevaBurdina2014InVE,
  title={In Vivo Effects of Diosgenin on the Activity of Some Drug-metabolizing Enzyme Systems},
  author={Magdalena Spasova Kondeva-Burdina and Ilina Nikolaeva Krasteva and Stefan Nikolov and Mitka Mitcheva},
  year={2014}
}
This study investigated the in vivo effect of Diosgenin, isolated from Asparagus officinalis, on the total quantity of Cytochrome P450, the activity of some enzymes Ethylmorphine N-demethylase (marker for CYP3A) and Aniline Hydroxylase (marker for CYP2E1), the quantity of malondialdehyde and reduced glutathione compared to Phenobarbital in rats. Diosgenin… CONTINUE READING