In Vivo Analysis of MEF2 Transcription Factors in Synapse Regulation and Neuronal Survival

Abstract

MEF2 (A-D) transcription factors govern development, differentiation and maintenance of various cell types including neurons. The role of MEF2 isoforms in the brain has been studied using in vitro manipulations with only MEF2C examined in vivo. In order to understand specific as well as redundant roles of the MEF2 isoforms, we generated brain-specific… (More)
DOI: 10.1371/journal.pone.0034863

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