In Vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch

@inproceedings{Hanke2011InVI,
  title={In Vitro impairment of whole blood coagulation and platelet function by hypertonic saline hydroxyethyl starch},
  author={Alexander Alfons Hanke and Stephanie Maschler and Herbert Sch{\"o}chl and Felix Fl{\"o}ricke and Klaus Goerlinger and Klaus Zanger and Peter Kienbaum},
  booktitle={Scandinavian journal of trauma, resuscitation and emergency medicine},
  year={2011}
}
BACKGROUND Hypertonic saline hydroxyethyl starch (HH) has been recommended for first line treatment of hemorrhagic shock. Its effects on coagulation are unclear. We studied in vitro effects of HH dilution on whole blood coagulation and platelet function. Furthermore 7.2% hypertonic saline, 6% hydroxyethylstarch (as ingredients of HH), and 0.9% saline solution (as control) were tested in comparable dilutions to estimate specific component effects of HH on coagulation. METHODS The study was… CONTINUE READING
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