In Vitro Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome

@article{Elzagallaai2009InVT,
  title={In Vitro Testing for the Diagnosis of Anticonvulsant Hypersensitivity Syndrome},
  author={Abdelbaset A. Elzagallaai and Sandra R. Knowles and Michael John Rieder and John Richard Bend and Neil H. Shear and Gideon Koren},
  journal={Molecular Diagnosis & Therapy},
  year={2009},
  volume={13},
  pages={313-330}
}
Anticonvulsant hypersensitivity syndrome (AHS) is a rare and potentially fatal reaction that develops in susceptible patients following exposure to certain drugs, including aromatic anticonvulsants. Because of its ill-defined clinical picture and resemblance to other diseases, the diagnosis of AHS is often difficult and requires a safe and reliable diagnostic test. Other than systemic rechallenge, which is not always ethically permissible and has its own limitations, no reliable diagnostic test… CONTINUE READING

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