In Vitro Spoilation of Silicone-Hydrogel Soft Contact Lenses in a Model-Blink Cell

@article{Peng2015InVS,
  title={In Vitro Spoilation of Silicone-Hydrogel Soft Contact Lenses in a Model-Blink Cell},
  author={Cheng-Chun Peng and Neil P. Fajardo and Trust T. Razunguzwa and Clayton J. Radke},
  journal={Optometry and Vision Science},
  year={2015},
  volume={92},
  pages={768–780}
}
PurposeWe developed an in vitro model-blink cell that reproduces the mechanism of in vivo fouling of soft contact lenses. In the model-blink cell, model tear lipid directly contacts the lens surface after forced aqueous rupture, mirroring the pre–lens tear-film breakup during interblink. MethodsSoft contact lenses are attached to a Teflon holder and immersed in artificial tear solution with protein, salts, and mucins. Artificial tear-lipid solution is spread over the air/tear interface as a… 
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