In-Vitro Screening of Phyllanthus Amarus and Eclipta Alba Against Leptospira Autumnalis

@article{Mohan2016InVitroSO,
  title={In-Vitro Screening of Phyllanthus Amarus and Eclipta Alba Against Leptospira Autumnalis},
  author={Arthi Mohan},
  journal={journal of medical science and clinical research},
  year={2016}
}
  • A. Mohan
  • Published 26 May 2016
  • Medicine
  • journal of medical science and clinical research
Background and Study Aims: Multi-drug resistance is one of the major public health problems especially in developing countries where relatively easy availability and higher consumption of medicines have lead to disproportionately higher incidence of inappropriate use of antibiotics and greater levels of resistance compared to developed countries. Leptospirosis is the most wide spread zoonoses in the world and recognized as an important public health problem. Aim and Methods: To extract and… 
The Effect of Environmental Stresses on lipL32 Gene Expression in Pathogenic Leptospira spp. through Real-Time PCR
TLDR
Temperature and pH stresses could lead to differences in the expression level and cause the lipL32 gene expression decrease in three pathogenic isolates, and the MIC results showed anti-leptospiral effect of Ph. amarus plant extract.

References

SHOWING 1-10 OF 21 REFERENCES
In vitro Evaluation of Eclipta alba against Serogroups of Leptospira interrogans
TLDR
The present study comprises the importance and utilization of traditional based medicines to overcome the adverse reaction by conventional drugs and standardize the technology in the field of Leptospirosis.
Antileptospiral activity of xanthones from Garcinia mangostana and synergy of gamma-mangostin with penicillin G
TLDR
Crude extracts and purified xanthones from fruit pericarp of G. mangostana with significant antibacterial activity may be used to control leptospirosis and the combination of xanthone with antibiotic enhances the antileptospiral efficacy.
Cytomorphological Changes and Inhibition of Inclusion Body Formation in Leptospira interrogans on Treatment with the Extracts of Adhatoda vasica
TLDR
It was found that the medicine used by traditional healers to cure liver disorders has very effective inhibition activity over the microbe responsible for Leptospirosis, and an alternate phytotheraphy can be recommended and the bioactive compound present in leaves of A.vasica has to be identified.
Phytochemicals, mineral content and antimicrobial screening of Phyllanthus amarus Schum and Thonn in Abuja, Nigeria
TLDR
The phytochemical screening of the leaves, stem, seed and root of P. amarus shows the presence of terpenoids and the results of the antimicrobial screening showed activities against P. auregenosa, E. coli, S. aUREus and C. albican at minimum inhibitory concentration as low as 100 ppm.
Research Letter - Preliminary screening of some folklore medicinal plants from Western India for potential antimicrobial activity
TLDR
There is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases from other sources, such as plants, may be a new source of antimicrobial agents possibly with novel mechanisms of action.
Antimicrobial activity of Phyllanthus amarus on some human intestinal facultatively anaerobic flora
Phyllanthus amarus is a small erect, annual monoecious glabous herb that grows to 30-40 cm in height. [1] It belongs to the family Euphorbiaceae with leaves that alternate distichous and crowded
In Vitro Sensitivity and Resistance of 46 Leptospira Strains Isolated from Rats in the Philippines to 14 Antimicrobial Agents
TLDR
In vitro susceptibilities of Leptospira isolates from rats to 14 antimicrobial agents will help in selecting effective and ineffective antimicrobials for treatment of leptospirosis and for the development of new selective media, respectively.
In vitro susceptibilities of five Leptospira strains to 16 antimicrobial agents
TLDR
In tests for minimal bactericidal concentration, ceftizoxime and cefotaxime were found to be more effective than penicillin G, streptomycin, tetracycline, ampicillin, andcefmetazole.
Study on the Prevalence of Leptospirosis among Fever Cases Reported from Private Clinics in the Urban areas of Villupuram District, Tamil Nadu, India
TLDR
It was quantified that 4% of cases reported in private clinics among fever cases and its findings ascertained both the importance of differential diagnosis as well as reports that should be included to the Government for knowing its real magnitude for planning.
Antimicrobial resistance in India: A review
TLDR
The situational analysis of antimicrobial resistance with respect to its problem, determinants and challenges ahead with strategies required in future to reduce the burden in India is discussed.
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