In Vitro Generation of Monocyte-Derived Macrophages under Serum-Free Conditions Improves Their Tumor Promoting Functions

@inproceedings{ReyGiraud2012InVG,
  title={In Vitro Generation of Monocyte-Derived Macrophages under Serum-Free Conditions Improves Their Tumor Promoting Functions},
  author={Flora Rey-Giraud and M. R. Hafner and Carola H Ries},
  booktitle={PloS one},
  year={2012}
}
The tumor promoting role of M2 macrophages has been described in in vivo models and the presence of macrophages in certain tumor types has been linked to a poor clinical outcome. In light of burgeoning activities to clinically develop new therapies targeting tumor-associated macrophages (TAMs), reliable in vitro models faithfully mimicking the tumor promoting functions of TAMs are required. Generation and activation of human monocyte-derived macrophages (MDM) in vitro, described as M1 or M2… CONTINUE READING
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References

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Showing 1-10 of 35 references

Expression of the inhibitory CD200 receptor is associated with alternative macrophage activation

N Koning, EM van, W Pouwels, MS Brouwer, D Voehringer
J Innate Immun • 2010
View 5 Excerpts
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Macrophage activation and polarization.

Frontiers in bioscience : a journal and virtual library • 2008
View 7 Excerpts
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Monocyte recruitment during infection and inflammation

Nature Reviews Immunology • 2011
View 1 Excerpt

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