In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes

  title={In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes},
  author={Alberto Arag{\'o}n-Muriel and Yamil Liscano and Yulieth A Upegui and Sara Maria Robledo and Mar{\'i}a Teresa Ram{\'i}rez-Apan and David Morales-Morales and Jos{\'e} O{\~n}ate-Garz{\'o}n and Dorian Polo-Cer{\'o}n},
Metal-based drugs, including lanthanide complexes, have been extremely effective in clinical treatments against various diseases and have raised major interest in recent decades. Hence, in this work, a series of lanthanum (III) and cerium (III) complexes, including Schiff base ligands derived from (1H-benzimidazol-2-yl)aniline, salicylaldehyde, and 2,4-dihydroxybenzaldehyde were synthesized and characterized using different spectroscopic methods. Besides their cytotoxic activities, they were… Expand
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