In Vitro Effects of Plasma Collected From Rats Administered Naftopidil on Whole Urinary Bladder Preparation Isolated From Rats

@article{Hattori2019InVE,
  title={In Vitro Effects of Plasma Collected From Rats Administered Naftopidil on Whole Urinary Bladder Preparation Isolated From Rats},
  author={T. Hattori and K. Sugaya and S. Nishijima and K. Kadekawa and T. Ueda and H. Yamamoto},
  journal={International Neurourology Journal},
  year={2019},
  volume={23},
  pages={277 - 286}
}
  • T. Hattori, K. Sugaya, +3 authors H. Yamamoto
  • Published 2019
  • Medicine
  • International Neurourology Journal
  • Purpose Alpha-1-adrenoceptor blockers (e.g., naftopidil) are prescribed for the treatment of male lower urinary tract symptoms. Although the mechanism of action of naftopidil has been studied in various organs, that in the urinary bladder remains unknown. To clarify the direct effects of naftopidil on this organ, activities were assessed in the isolated rat whole urinary bladder. Methods A total of 30 female rats were used. In Experiment 1, bladder activity was measured during a cumulative… CONTINUE READING

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