In Vitro Effect of Knotolan, a New Lignan from Abies sibirica, on the Growth of Hormone-Dependent Breast Cancer Cells

Here we present antiestrogenic effects of Knotolan®, a new dietary lignan from Abies sibirica raw material. Knotolan abolished growth-stimulating effects of 17β-estragiol on hormonedependent MCF-7 cells.