In Vitro Characterization of a Multifunctional Staphylokinase Variant with Reduced Reocclusion, Produced from Salt Inducible E. coli GJ1158

@inproceedings{Pulicherla2013InV,
  title={
In Vitro Characterization of a Multifunctional Staphylokinase Variant with Reduced Reocclusion, Produced from Salt Inducible E. coli GJ1158},
  author={K. K. Pulicherla and A Suneel Kumar and Gopi S Gadupudi and Seetha Ram Kotra and K. R. S. Sambasiva Rao},
  booktitle={BioMed research international},
  year={2013}
}
The thrombolytic therapy with clinically approved drugs often ensues with recurrent thrombosis caused by thrombin-induced platelet aggregation from the clot debris. In order to minimize these problems, a staphylokinase (SAK)-based bacterial friendly multifunctional recombinant protein SRH (staphylokinase (SAK) linked with tripeptide RGD and dodecapeptide Hirulog (SRH)) was constructed to have Hirulog as an antithrombin agent and RGD (Arg-Gly-Asp) as an antiplatelet agent in the present study… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 35 references

European Cardiovascular Disease Statistics 2012, European Heart Network, European Society of Cardiology

  • M. Nichols, N. Townsend, P. Scarborough
  • Brussels, Belgium,
  • 2012
1 Excerpt

Cloning and expression of a new recombinant thrombolytic and anthithrombotic agent — a staphylokinase variant

  • J. Wang
  • Acta Biochimica Polonica
  • 2009

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