In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates

@article{Rothman2003InVC,
  title={In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates},
  author={Richard B. Rothman and Nga Vu and John S. Partilla and Bryan L. Roth and Sandra J. Hufeisen and Beth A Compton-Toth and Jon Birkes and Richard Young and Richard A Glennon},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2003},
  volume={307},
  pages={138 - 145}
}
  • R. Rothman, Nga Vu, R. Glennon
  • Published 1 October 2003
  • Biology, Chemistry
  • Journal of Pharmacology and Experimental Therapeutics
Ephedrine is a long-studied stimulant available both as a prescription and over-the-counter medication, as well as an ingredient in widely marketed herbal preparations, and is also used as a precursor for the illicit synthesis of methamphetamine. Ephedrine is related to phenylpropanolamine, a decongestant removed from the market place due to concerns that its use increased the risk of hemorrhagic stroke. Standard pharmacology texts emphasize that ephedrine is both a direct and indirect… 

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