In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates

@article{Rothman2003InVC,
  title={In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates},
  author={R. Rothman and Nga Vu and J. Partilla and B. Roth and S. J. Hufeisen and B. Compton-Toth and Jon Birkes and R. Young and R. Glennon},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2003},
  volume={307},
  pages={138 - 145}
}
  • R. Rothman, Nga Vu, +6 authors R. Glennon
  • Published 2003
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental Therapeutics
  • Ephedrine is a long-studied stimulant available both as a prescription and over-the-counter medication, as well as an ingredient in widely marketed herbal preparations, and is also used as a precursor for the illicit synthesis of methamphetamine. Ephedrine is related to phenylpropanolamine, a decongestant removed from the market place due to concerns that its use increased the risk of hemorrhagic stroke. Standard pharmacology texts emphasize that ephedrine is both a direct and indirect… CONTINUE READING
    157 Citations

    Paper Mentions

    Interventional Clinical Trial
    The specific aim of this study is to determine whether water ingestion potentiates the pressor response to pseudoephedrine in patients with primary disorders of autonomic failure… Expand
    ConditionsMultiple System Atrophy, Shy-Drager Syndrome
    InterventionDrug, Other
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