In Vitro Antifungal Activity of Epigallocatechin 3-O-Gallate against Clinical Isolates of Dermatophytes

@article{Park2011InVA,
  title={In Vitro Antifungal Activity of Epigallocatechin 3-O-Gallate against Clinical Isolates of Dermatophytes},
  author={Bong Joo Park and Hideaki Taguchi and Katsuhiko Kamei and Tetsuhiro Matsuzawa and Suong-hyu Hyon and Jong-Chul Park},
  journal={Yonsei Medical Journal},
  year={2011},
  volume={52},
  pages={535 - 538}
}
Previously, we reported that epigallocatechin 3-O-gallate (EGCg) has growth-inhibitory effect on clinical isolates of Candida species. In this study, we investigated the antifungal activity of EGCg and antifungal agents against thirty-five of dermatophytes clinically isolated by the international guidelines (M38-A2). All isolates exhibited good susceptibility to EGCg (MIC50, 2-4 µg/mL, MIC90, 4-8 µg/mL, and geometric mean (GM) MICs, 3.36-4 µg/mL) than those of fluconazole (MIC50, 2-16 µg/mL… Expand
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