In This Issue

@article{2006InTI,
  title={In This Issue},
  author={},
  journal={Cell},
  year={2006},
  volume={125},
  pages={1-3}
}
The complement cascade is a branch of the immune system involved in pathogen clearance. In the classical pathway, pathogen recognition by antibodies leads to their interaction with complement component C1q, an activation of proteases. Cleavage of the complement protein C3 and deposition of C3 fragments on the pathogen follow, allowing pathogen clearance by the immune system. In this paper, Kang et al. identify an antibody-independent complement pathway that involves SIGN-R1, a lectin expressed… CONTINUE READING
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