In Situ Identification of CD44+/CD24− Cancer Cells in Primary Human Breast Carcinomas

@inproceedings{Perrone2012InSI,
  title={In Situ Identification of CD44+/CD24− Cancer Cells in Primary Human Breast Carcinomas},
  author={Giuseppina Perrone and Laura Maria Gaeta and Mariagiovanna Zagami and Francesca Nasorri and Roberto Coppola and Domenico Borzomati and Francesco Bartolozzi and Vittorio Altomare and Lucio Trodella and Giuseppe Tonini and Donatella Santini and Andrea Cavani and Andrea Onetti Muda},
  booktitle={PloS one},
  year={2012}
}
Breast cancer cells with the CD44+/CD24- phenotype have been reported to be tumourigenic due to their enhanced capacity for cancer development and their self-renewal potential. The identification of human tumourigenic breast cancer cells in surgical samples has recently received increased attention due to the implications for prognosis and treatment, although limitations exist in the interpretation of these studies. To better identify the CD44+/CD24- cells in routine surgical specimens, 56… CONTINUE READING

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