In Situ Blood–Brain Barrier Transport of Nanoparticles

@article{Koziara2003InSB,
  title={In Situ Blood–Brain Barrier Transport of Nanoparticles},
  author={Joanna M. Koziara and Paul R. Lockman and David D. Allen and Russell J. Mumper},
  journal={Pharmaceutical Research},
  year={2003},
  volume={20},
  pages={1772-1778}
}
Purpose. Two novel types of nanoparticles were evaluated as potential carriers for drugs across the blood–brain barrier (BBB). Methods. Nanoparticles were composed of biocompatible materials including emulsifying wax (E. Wax) or Brij 72. Brij 78 and Tween 80 were used as surfactants for E.Wax nanoparticles (E78 NPs) and Brij 72 nanoparticles (E72 NPs), respectively. Both nanoparticle formulations were prepared from warm microemulsion precursors using melted E. Wax or Brij 72 as the oil phase… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

The effect of iron nanoparticles on performance of cognitive tasks in rats.

Environmental science and pollution research international • 2017
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Nanoparticulate systems for brain delivery of drugs.

Advanced drug delivery reviews • 2001
View 7 Excerpts
Highly Influenced

Pardridge. Brain Drug Targeting, The Future of Brain Drug Development

W M.
2001
View 4 Excerpts
Highly Influenced

Engineering tumortargeted gadolinium hexanedione nanoparticles for potential application in neutron capture therapy

R. J. Mumper
Bioconjugate Chem . • 2002

Similar Papers

Loading similar papers…