In Silico Performance of a Recellularized Tissue Engineered Transcatheter Aortic Valve.

@article{Noble2019InSP,
  title={In Silico Performance of a Recellularized Tissue Engineered Transcatheter Aortic Valve.},
  author={Christopher Isaac Noble and Joshua A Choe and Susheil Uthamaraj and Milton Deherrera and Amir Lerman and Melissa D Young},
  journal={Journal of biomechanical engineering},
  year={2019}
}
Commercially available heart valves have many limitations, such as a lack of re-modeling, risk of calcification and thromboembolic problems. Many state-of-the-art tissue engineered heart valves rely on recellularization. Current in vitro testing is insufficient in characterizing a soon to be living valve. It is imperative to understand the performance of an in situ valve, but due to the complex in vivo environment this is difficult to accomplish. Finite element analysis has become a standard… CONTINUE READING
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