In Silico Design of a Chimeric Protein Containing Antigenic Fragments of Helicobacter pylori; A Bioinformatic Approach

@article{Mohammad2016InSD,
  title={In Silico Design of a Chimeric Protein Containing Antigenic Fragments of Helicobacter pylori; A Bioinformatic Approach},
  author={Nazanin Mohammad and Mehrnaz Taghipour Karsabet and J. Amani and A. Ardjmand and Mohsen Razavi Zadeh and M. Gholi and M. Saffari and A. Ghasemi},
  journal={The Open Microbiology Journal},
  year={2016},
  volume={10},
  pages={97 - 112}
}
Helicobacter pylori is a global health problem which has encouraged scientists to find new ways to diagnose, immunize and eradicate the H. pylori infection. In silico studies are a promising approach to design new chimeric antigen having the immunogenic potential of several antigens. In order to obtain such benefit in H. pylori vaccine study, a chimeric gene containing four fragments of FliD sequence (1-600 bp), UreB (327-334 bp),VacA (744-805 bp) and CagL(51-100 bp) which have a high density… Expand

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A novel design of a multi-antigenic, multistage and multi-epitope vaccine against Helicobacter pylori: An in silico approach.
Structural analysis of the flagellar capping protein FliD from Helicobacter pylori.
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