In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

@article{Riyaphan2021InSA,
  title={In Silico Approaches to Identify Polyphenol Compounds as $\alpha$-Glucosidase and $\alpha$-Amylase Inhibitors against Type-II Diabetes},
  author={Jirawat Riyaphan and Dinh-Chuong Pham and Max K. Leong and Ching-Feng Weng},
  journal={Biomolecules},
  year={2021},
  volume={11}
}
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose with surplus adverse effects, leading to efforts devoted to urgently seeking new anti-diabetes drugs from natural sources for delayed starch digestion. This review attempts to explore 10 families e.g., Bignoniaceae, Ericaceae, Dryopteridaceae… 

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