In African American type 2 diabetic patients, is vitamin D deficiency associated with lower blood levels of hydrogen sulfide and cyclic adenosine monophosphate, and elevated oxidative stress?

@article{Jain2013InAA,
  title={In African American type 2 diabetic patients, is vitamin D deficiency associated with lower blood levels of hydrogen sulfide and cyclic adenosine monophosphate, and elevated oxidative stress?},
  author={Sushil K. Jain and Prasenjit Manna and David Micinski and Benjamin J. Lieblong and Gunjan Kahlon and Lester Morehead and Robert Daniel Hoeldtke and Pat Farrington Bass and Steven N Levine},
  journal={Antioxidants & redox signaling},
  year={2013},
  volume={18 10},
  pages={1154-8}
}
African Americans (AA) have a higher incidence of cardiovascular disease and vitamin D (VD) deficiency compared with Caucasians. Hydrogen sulfide (H(2)S) is an important signaling molecule. This study examined the hypothesis that blood levels of H(2)S are lower in AA type 2 diabetic patients (T2D). Fasting blood was obtained from T2D and healthy controls. Results showed a significant decrease in plasma levels of cyclic adenosine monophosphate (cAMP) and H(2)S in AA T2D but not in Caucasian T2D… CONTINUE READING