In‐vitro mutagenic potential and effect on permeability of co‐administered drugs across Caco‐2 cell monolayers of Rubus idaeus and its fortified fractions

@article{Kreander2006InvitroMP,
  title={In‐vitro mutagenic potential and effect on permeability of co‐administered drugs across Caco‐2 cell monolayers of Rubus idaeus and its fortified fractions},
  author={K. Kreander and A. Galkin and Satu Vuorela and P. Tammela and L. Laitinen and M. Heinonen and P. Vuorela},
  journal={Journal of Pharmacy and Pharmacology},
  year={2006},
  volume={58}
}
  • K. Kreander, A. Galkin, +4 authors P. Vuorela
  • Published 2006
  • Chemistry, Medicine
  • Journal of Pharmacy and Pharmacology
  • This study investigated the mutagenic, anti‐mutagenic and cytotoxic effects of acetone extract of raspberry, Rubus idaeus L. (v. Ottawa) Rosaceae, and the isolated and characterized ellagitannin and anthocyanin fractions thereof, suitable for food applications. The studied raspberry extract and fractions did not show any mutagenic effects determined in the miniaturized Ames test and were not cytotoxic to Caco‐2 cells at the used concentrations. However, the anti‐mutagenic properties were… CONTINUE READING
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