In vitro comparative analysis of antiproliferative activity of essential oil from mandarin peel and its principal component limonene.

@article{Manassero2013InVC,
  title={In vitro comparative analysis of antiproliferative activity of essential oil from mandarin peel and its principal component limonene.},
  author={Carlos A Manassero and Juan R. Girotti and Sergio Javier Mijailovsky and Margarita Garc{\'i}a Garc{\'i}a de Bravo and M{\'o}nica Patricia Polo},
  journal={Natural product research},
  year={2013},
  volume={27 16},
  pages={1475-8}
}
The effects of the essential oil of mandarin peel (Corrientes, Argentina) and limonene (its major component) were studied on two human tumour cell lines growth (lung adenocarcinoma A549 and hepatocarcinoma HepG2). The essential oil was obtained by cold press and its composition was investigated by gas chromatography (GC) and GC/mass spectrometry (MS) analysis. The antiproliferative effect was studied using an MTT assay. Both mandarin essential oil and limonene tested showed a strong dose… CONTINUE READING

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