Imunocompetent Mice Model for Dengue Virus Infection

  title={Imunocompetent Mice Model for Dengue Virus Infection},
  author={Denise Gonçalves and Rafael de Queiroz Prado and Eric Almeida Xavier and Nat{\'a}lia Cristina de Oliveira and Paulo Marcos da Matta Guedes and Jo{\~a}o Santana da Silva and Luiz Tadeu Moraes Figueiredo and Victor Hugo Aquino},
Dengue fever is a noncontagious infectious disease caused by dengue virus (DENV). DENV belongs to the family Flaviviridae, genus Flavivirus, and is classified into four antigenically distinct serotypes: DENV-1, DENV-2, DENV-3, and DENV-4. The number of nations and people affected has increased steadily and today is considered the most widely spread arbovirus (arthropod-borne viral disease) in the world. The absence of an appropriate animal model for studying the disease has hindered the… CONTINUE READING
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