Imputation strategies for blood pressure data nonignorably missing due to medication use.

@article{Cook2006ImputationSF,
  title={Imputation strategies for blood pressure data nonignorably missing due to medication use.},
  author={Nancy R. Cook},
  journal={Clinical trials},
  year={2006},
  volume={3 5},
  pages={411-20}
}
BACKGROUND Underlying or untreated blood pressure (BP) is often an outcome of interest, but is unobservable when study participants are on anti-hypertensive medications. Untreated levels are not missing at random but would be higher among those on such medication. In such cases, standard methods of analysis may lead to bias. PURPOSE BPs obtained at the private physician's office (out-of-study BPs) at the time of prescription of anti-hypertensive medications were available from Phase II of the… CONTINUE READING