Impulsive Choice Induced in Rats by Lesions of the Nucleus Accumbens Core

@article{Cardinal2001ImpulsiveCI,
  title={Impulsive Choice Induced in Rats by Lesions of the Nucleus Accumbens Core},
  author={R. Cardinal and David R. Pennicott and C. Lakmali and Sugathapala and T. Robbins and B. Everitt},
  journal={Science},
  year={2001},
  volume={292},
  pages={2499 - 2501}
}
  • R. Cardinal, David R. Pennicott, +3 authors B. Everitt
  • Published 2001
  • Medicine, Psychology
  • Science
  • Impulsive choice is exemplified by choosing a small or poor reward that is available immediately, in preference to a larger but delayed reward. Impulsive choice contributes to drug addiction, attention-deficit/hyperactivity disorder, mania, and personality disorders, but its neuroanatomical basis is unclear. Here, we show that selective lesions of the nucleus accumbens core induce persistent impulsive choice in rats. In contrast, damage to two of its afferents, the anterior cingulate cortex and… CONTINUE READING
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