Impulse control disorders in advanced Parkinson's disease with dyskinesia: The ALTHEA study

  title={Impulse control disorders in advanced Parkinson's disease with dyskinesia: The ALTHEA study},
  author={Roberta Biundo and Luca Weis and Giovanni Abbruzzese and Giovanna Calandra-Buonaura and Pietro Cortelli and Maria Cristina Jori and Leonardo Lopiano and R. Marconi and Angela Matinella and Francesca Morgante and Alessandra Nicoletti and Tiziano Tamburini and Michele Tinazzi and Mario Zappia and Ruxandra Julia Vorovenci and Angelo Antonini},
  journal={Movement Disorders},
Impulse control disorders and dyskinesia are common and disabling complications of dopaminergic treatment in Parkinson's disease. They may coexist and are possibly related. The objectives of this study were to assess the frequency and severity of impulse control disorders in Parkinson's disease patients with dyskinesia. 

Suggestive association between OPRM1 and impulse control disorders in Parkinson's disease

The aim of this study was to identify candidate gene variants associated with impulse control disorders and related behaviors in Parkinson's disease.

Genetic prediction of impulse control disorders in Parkinson's disease

To develop a clinico‐genetic predictor of impulse control disorder (ICD) risk in Parkinson's disease (PD) risk, a large number of genes from four previous studies are examined.

Impulse Control Disorders and Levodopa-Induced Dyskinesias in Parkinson's Disease: Pulsatile versus Continuous Dopaminergic Stimulation.

PD patients with LID show I CRB more frequently and more severely than patients without LID, suggesting a potential protective effect of JLI on ICRB.

Impulse control disorders in Parkinson disease and RBD A longitudinal study of severity

The prevalence, natural history, and risk factors for impulse control behaviors (ICBs) among people with Parkinson disease, those with REM sleep behavior disorder (RBD), and controls are described.

Impact of Subthalamic Deep Brain Stimulation on Impulse Control Disorders in Parkinson's Disease: A Prospective Study

Impact of subthalamic deep brain stimulation (DBS) on impulse control disorders (ICD) in Parkinson's disease (PD) remains controversial.

Impulse Control Disorders in Parkinson’s disease

The epidemiology, genetic risk and long-term trajectory of ICDs in PD was described and it was found that ICD status in patients was independently associated with dopamine agonist treatment and depressive symptoms, while additional analyses on the PD cohort did not find any association between I CD status and presence of psychotic symptoms.

MRI of Motor and Nonmotor Therapy‐Induced Complications in Parkinson's Disease

An overview of structural and functional brain changes associated with motor and nonmotor therapy‐induced complications in Parkinson's disease is presented and magnetic resonance imaging may offer structural and/or functional neuroimaging biomarkers that could be used as predictive signs of development, maintenance, and progression of these complications.

The factors associated with impulse control behaviors in Parkinson's disease: A 2‐year longitudinal retrospective cohort study

A longitudinal assessment of the remission, persistence, and development of ICB and those associated factors in patients with PD and the associated factors have been little known.

Impulse Control Disorders in Parkinson's Disease. A Brief and Comprehensive Review

The prevalence of ICDs, the risk factors, its pathophysiological mechanisms, the link with agonist dopaminergic therapies and therapeutic managements are presented.



Impulse control disorders and levodopa-induced dyskinesias in Parkinson's disease: an update

Impulsivity and compulsivity in drug‐naïve patients with Parkinson's disease

  • A. AntoniniC. Siri P. Barone
  • Psychology, Biology
    Movement disorders : official journal of the Movement Disorder Society
  • 2011
Impulsivity and compulsive symptoms have never been explored in PD patients before initiation of DRT, and a 20% of impulse control disorders (ICD) in an Italian cohort was reported.

Unawareness of dyskinesias in Parkinson's and Huntington's diseases

In PD the unawareness seems to be inversely related with severity of dyskinesias, while in HD it is directly related to disease duration and severity.

Impulse control disorders in parkinson disease: A multicenter case–control study

To assess factors associated with impulse control disorders (ICDs) in Parkinson disease (PD) using a multicenter case–control design, a network-based approach is used.

Impulsive behavior and associated clinical variables in Parkinson's disease.

Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease.

D dopaminergic side effects in Parkinson's disease are associated with oscillatory activity in the theta-alpha band, but at different frequencies and with different topography for the motor (dyskinesias) and behavioural (abnormal impulsivity) manifestations.

Impulse control disorder related behaviours during long‐term rotigotine treatment: a post hoc analysis

The frequency of ICD behaviours reported as adverse events in long‐term studies of rotigotine transdermal patch in PD was evaluated.